KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
9.09
Human Site:
S1493
Identified Species:
15.38
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
S1493
P
R
E
H
Q
T
G
S
A
R
S
E
G
Y
Y
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S1493
P
R
E
H
Q
T
G
S
A
R
S
E
G
Y
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
D1131
P
I
S
K
K
E
K
D
R
Y
L
D
V
C
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
C1765
I
R
E
H
V
T
G
C
A
R
S
E
G
F
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
S1088
K
L
K
Y
L
N
N
S
R
A
F
A
D
E
P
Chicken
Gallus gallus
Q5F3P8
2008
223067
C1788
M
R
E
H
V
T
G
C
A
R
S
E
G
Y
Y
Frog
Xenopus laevis
Q66J90
1938
216239
C1718
L
R
E
H
V
T
G
C
A
R
S
E
G
Y
Y
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
C1626
I
R
D
H
V
T
G
C
A
R
S
E
G
Y
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
C1412
L
I
R
H
K
T
G
C
A
R
T
E
G
F
Y
Honey Bee
Apis mellifera
XP_395451
1406
159180
G1207
N
D
V
E
D
N
N
G
S
Y
A
S
G
D
G
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
V1308
M
K
Q
K
R
S
L
V
R
R
P
D
N
E
S
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
S1742
S
R
V
H
L
S
G
S
S
R
T
E
G
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
R881
Y
T
P
E
L
C
Q
R
E
E
S
S
N
K
E
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
A1114
N
G
N
T
N
S
V
A
A
A
A
E
A
A
R
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
6.6
N.A.
73.3
N.A.
N.A.
6.6
80
80
73.3
N.A.
53.3
6.6
6.6
60
P-Site Similarity:
100
100
N.A.
20
N.A.
80
N.A.
N.A.
20
80
80
80
N.A.
73.3
20
40
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
58
15
15
8
8
8
0
% A
% Cys:
0
0
0
0
0
8
0
36
0
0
0
0
0
8
0
% C
% Asp:
0
8
8
0
8
0
0
8
0
0
0
15
8
8
0
% D
% Glu:
0
0
36
15
0
8
0
0
8
8
0
65
0
15
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
15
0
% F
% Gly:
0
8
0
0
0
0
58
8
0
0
0
0
65
0
8
% G
% His:
0
0
0
58
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
8
15
15
0
8
0
0
0
0
0
0
8
0
% K
% Leu:
15
8
0
0
22
0
8
0
0
0
8
0
0
0
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
8
0
8
15
15
0
0
0
0
0
15
0
0
% N
% Pro:
22
0
8
0
0
0
0
0
0
0
8
0
0
0
15
% P
% Gln:
0
0
8
0
15
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
50
8
0
8
0
0
8
22
65
0
0
0
0
8
% R
% Ser:
8
0
8
0
0
22
0
29
15
0
50
15
0
0
8
% S
% Thr:
0
8
0
8
0
50
0
0
0
0
15
0
0
0
0
% T
% Val:
0
0
15
0
29
0
8
8
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
0
0
15
0
0
0
43
58
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _